Scientific Name(s): Cymbopogon citratus (DC.) Stapf., C. flexuosus (Nees ex Stend.) J.F. Watson. Family: Poaceae (grasses)

Common Name(s): Lemongrass , achara (tea).


Lemongrass is used as a fragrance and flavoring and for a wide variety of ailments in folk medicine. However, clinical trials are lacking to support these uses. Limited studies have demonstrated antifungal and insecticide efficacy, as well as potential anticarcinogenic activity, while suggested hypotensive and hypoglycemic actions have not been confirmed.


Information from clinical trials is lacking.


Contraindications have not yet been identified.


Information regarding safety and efficacy in pregnancy and lactation is lacking. Avoid use.


None well documented.

Adverse Reactions

Rare cases of hypersensitivity have been reported. Toxic alveolitis has been associated with inhalation of the oil.


Lemongrass is considered to be of low toxicity at low doses.


Cymbopogon is a tall, aromatic perennial grass that is native to tropical Asia. C. citratus is known as Guatemala, West Indian, or Madagascar lemongrass. C. flexuosus is known as cochin lemongrass, British Indian lemongrass, East Indian lemongrass, or French Indian verbena. C. citratus is cultivated in the West Indies, Central and South America, and tropical regions. The linear leaves can grow up to 90 cm in height and 5 mm in width. Freshly cut and partially dried leaves are used medicinally and are the source of the essential oil. ,


Lemongrass is usually ingested as an infusion made by pouring boiling water on fresh or dried leaves and is one of the most widely used traditional plants in South American folk medicine. It is used as an antispasmodic, antiemetic, and analgesic, as well as for the management of nervous and GI disorders and the treatment of fevers. In India it is commonly used as an antitussive, antirheumatic, and antiseptic. It is usually ingested as an infusion made by pouring boiling water on fresh or dried leaves. In Chinese medicine, lemongrass is used in the treatment of headaches, stomach aches, abdominal pain, and rheumatic pain. Lemongrass is an important part of Southeast Asian cuisine, especially as flavoring in Thai food. Other uses include as an astringent and a fragrance in beauty products. , , ,


Fresh C. citratus grass contains approximately 0.4% volatile oil. The oil contains 65% to 85% citral, a mixture of 2 geometric isomers, geraniol and neral. Related compounds geraniol, geranic acid, and nerolic acid have also been identified. , , , , Other compounds found in the oil include myrcene (12% to 25%), diterpenes, methylheptenone, citronellol, linalol, farnesol, other alcohols, aldehydes, linalool, terpineol, and more than a dozen other minor fragrant components. , , Geographical variations in the chemical constituents have been noted. , ,

Nonvolatile components of C. citratus consist of luteolins, homo-orientin, chlorogenic acid, caffeic acid, p -coumaric acid, fructose, sucrose, octacosanol, and others. Flavonoids luteolin and 6-C-glucoside have also been isolated. ,

C. flexuosus volatile oil typically contains up to 85% citral. However, many strains have a higher concentration of geraniol (50%), with citral (10% to 20%) and methyl eugenol as minor components. Another type of East Indian lemongrass is reported to contain no citral but up to 30% borneol.

Uses and Pharmacology

Antimicrobial effects

Several reports describe antimicrobial effects of lemongrass, including activity against both gram-positive and gram-negative bacterial pathogens, and fungi. , , , , , , , , , , , The effects are attributed in part to the geraniol (alpha-citral) and neral (beta-citral) constituents. ,

Clinical data

Clinical trials are lacking, but in a 13-oil study, lemongrass oil was found to be among the most active against human dermatophyte strains, inhibiting 80% of strains, with inhibition zones more than 10 mm in diameter.

Anticarcinogenic effects
Animal data

Antimutagenic properties of ethanol lemongrass extracts against certain S. typhimurium strains have been demonstrated, while in other studies, the extract was shown to inhibit DNA adduct formation in rat colon but not liver cells. , In another experiment, ethanol extracts reduced the number but not the size of lesions in rat livers with induced hepatocellular carcinoma. Studies have demonstrated toxicity and apoptosis-inducing action of the essential oil and extracts against mouse and human leukemia cells, respectively. , ,

Topical C. citratus extract exhibited an antioxidant action in mouse skin, leading researchers to suggest its potential in skin cancer prevention.

Clinical data

Clinical trials are lacking.

Other uses

Conflicting analgesic and anti-inflammatory effects have been demonstrated in animal experiments, but most purported effects were too weak to be of clinical importance. , , ,

Antioxidant action

Lemongrass oil ( C. citratus ) has demonstrated antioxidant and radical-scavenging activity in several experiments. , ,


Dose-related hypotensive effects and weak diuretic actions have been demonstrated in rats. In one study, lemongrass extract reduced the cardiac rate but did not alter the contractile force in isolated rat hearts. Clinical trials are lacking.


A study found that lemongrass leaf tea ingested for 2 weeks induced no hypoglycemic changes ; however, an experiment in rats demonstrated dose-dependent decreases in fasting blood glucose levels.


The mosquito-repellent effect of lemongrass was evaluated in a study using Aedes aegypti adult mosquitoes and differing concentrations of lemongrass oil in liquid paraffin. Repellent activity was attributed to the citral content. Other experiments have evaluated the oil as an insecticide. , Clinical trials are lacking.


No information is available on dosage in the medicinal use of lemongrass oil. Lemongrass is Generally Recognized as Safe (GRAS) in the United States.

A suggested safe limit for humans (based on an experiment in rats) is 0.7 mg/kg/day of the essential oil.


Information is lacking. Citral and myrcene have been shown to induce maternal toxicity in pregnant rats at high dosages. Lemongrass extracts have demonstrated antimitotic and apoptotic action and should be avoided in pregnancy. ,


Citral, found in high concentrations in the essential oil of lemongrass, is a potent inducer of glutathione-S-transferase and its constituent beta-myrcene has been shown to interfere with cytochrome P450 liver enzymes; however, no drug interactions have been reported for lemongrass. ,

Adverse Reactions

Topical application of lemongrass has rarely led to an allergic reaction. Two cases of toxic alveolitis have been reported from inhalation of the oil.


An infusion of lemongrass given orally to male and pregnant female rats for 2 months in doses up to 20 times the corresponding human dose did not induce any toxic effects. No external malformations were noted in the pups. However, in another study, doses higher than 1,500 mg/kg body weight showed histological changes in the stomach and liver, leading to marked abnormalities in the liver and stomach mucosa and death of the experimental rats.

Achara, an herbal tea made from dried lemongrass leaves, was suggested to be atoxic in a small study. Beta-myrcene was found to be nontoxic in one report, but toxic in another. , Aqueous extracts of the plant used as an insecticide led to some mitotic abnormalities in Allium cepa root tips grown in these extracts.


1. Cymbopogon citratus (DC. ex Nees) Stapf. USDA, NRCS. 2008. The PLANTS Database. ( http://plants.usda.gov , 10 December 2008). National Plant Data Center, Baton Rouge, LA 70874-4490 USA.
2. Blumenthal, M, ed. The Complete German Commission E Monographs . Austin TX: American Botanical Council; 1998:341-342.
3. Leung AY. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics . New York, NY: Wiley; 1980.
4. Girón LM, Freire V, Alonzo A, Cáceres A. Ethnobotanical survey of the medicinal flora used by the Caribs of Guatemala. J Ethnopharmacol . 1991;34(2-3):173-187.
5. Leite JR, Seabra Mde L, Maluf E, et al. Pharmacology of lemongrass ( Cymbopogon citratus Strapf.) ΙΙΙ. Assessment of eventual toxic, hypnotic and anxiolytic effects on humans. J Ethnopharmacol . 1986;17(1):75-83.
6. Lewinsohn E, et al. Histochemical localization of citral accumulation in lemongrass leaves ( Cymbopogon citratus [DC.] Stapf., Poaceae). Ann Bot (London) . 1998;81:35-39.
7. Ming L, et al. Yield of essential oil of citral content in different parts of lemongrass leaves ( Cymbopogon citratus [DC.] Stapf.) Poaceae. Acta Hortic . 1996;426 (International Symposium on Medicinal and Aromatic Plants), 555-559.
8. Torres R. Citral from Cymbopogon citratus (DC) Stapf (lemongrass) oil. Philipp J Sci . 1993;122:269-287.
9. Sargenti S, et al. Supercritical fluid extraction of Cymbopogon citratus . Chromatographia . 1997;46:285-290.
10. Masuda T, Odaka Y, Ogawa N, Nakamoto K, Kuninaga H. Identification of geranic acid, a tyrosinase inhibitor in lemongrass ( Cymbopogon citratus ). J Agric Food Chem . 2008;56(2):597-601.
11. Kasumov F, et al. Components of the essential oil of Cymbopogon citratus Stapf. Khim Pnr Soedin . 1983;1:108-109.
12. Ansan S, et al. Thin layer gas liquid chromatographic analysis of lemongrass oil. Indian J Nat Prod . 1986;2:3-7.
13. Viturro C, et al. Composition of the essential oil of Cymbopogon citratus . An Asoc Quim Argent . 1998;86:45-48.
14. Torres R, et al. Chemical composition of the essential oil of Philippine Cymbopogon citratus (DC) Stapf. Philipp J Sci . 1996;125:147-156.
15. Faruq M, et al. TLC technique in the component characterization and quality determination of Bangladeshi lemongrass oil ( Cymbopogon citratus Stapf.) Bangladesh J Sci Ind Res . 1994;29:27-38.
16. Idrissi A, et al. Composition of the essential oil of lemongrass ( Cymbopogon citratus DC. Stapf) grown in Morocco. Plant Med Phytother . 1993;26:274-277.
17. De Matouschek. Phytochemical studies on non-volatile constituents of Cymbopogon citratus (DC.) Stapf grown in Morocco. Pharm Acta Helv . 1991;66:242-245.
18. Guanasingh C, et al. Flavonoids of Cymbopogon citratus . Indian J Pharm Sci . 1981;43:115.
19. Cheel J, Theoduloz C, Rodriguez J, Schmeda-Hirschmann G. Free radical scavengers and antioxidants from Lemongrass ( Cymbopogon citratus [DC.] Stapf.). J Agric Food Chem . 2005;53(7):2511-2517.
20. Ogunlana EO, Hoglund S, Onawunmi G, Skold O. Effects of lemongrass oil on the morphological characteristics and peptidoglycan synthesis of Escherichia coli cells. Microbios . 1987;50(202):43-59.
21. Baratta M, et al. Antimicrobial and antioxidant properties of some commercial essential oils. Flavour Fragrance J . 1998;13:235-244.
22. Onawunmi GO, Yisak WA, Ogunlana EO. Antibacterial constituents in the essential oil of Cymbopogon citratus (DC.) Stapf. J Ethnopharmacol . 1984;12(3):279-286.
23. Hammer KA, Carson CF, Riley TV. Antimicrobial activity of essential oils and other plant extracts. J Appl Microbiol . 1999;86(6):985-990.
24. Chalcat J, et al. Correlation between chemical composition and antimicrobial activity. VI. Activity of some African essential oils. J Essent Oil Res . 1997;9:67-75.
25. Wannissorn B, et al. Antifungal activity of lemon grass and lemon grass oil cream. Phytother Res . 1996;10:551-554.
26. Lima EO, Gompertz OF, Giesbrecht AM, Paulo MQ. In vitro antifungal activity of essential oils obtained from officinal plants against dermatophytes. Mycoses . 1993;36(9-10):333-336.
27. Qureshi S, Rai MK, Agrawal SC. In vitro evaluation of inhibitory nature of extracts of 18-plant species of Chhindwara against 3-keratinophilic fungi. Hindustan Antibiot Bull . 1997;39(1-4):56-60.
28. Yadav P, et al. Screening some essential oils against ringworm fungi. Indian J Pharm Sci . 1994;56:227-230.
29. Kishore N, Mishra AK, Chansouria JP. Fungitoxicity of essential oils against dermatophytes. Mycoses . 1993;36(5-6):211-215.
30. Mishra AK, Dubey NK. Evaluation of some essential oils for their toxicity against fungi causing deterioration of stored food commodities. Appl Environ Microbiol . 1994;60(4):1101-1105.
31. Helal GA, Sarhan MM, Abu Shahla AN, Abou El-Khair EK. Effects of Cymbopogon citratus L. essential oil on the growth, lipid content and morphogenesis of Aspergillus niger ML2-strain. J Basic Microbiol . 2006;46(6):456-469.
32. Syed M, et al. Essential oils of the family Gramineae with antibacterial activity. Part 2. The antibacterial activity of a local variety of Cymbopogon citratus oil and its dependence on the duration of storage. Pak J Sci Ind Res . 1995;38:146-148.
33. Vinitketkumnuen U, Puatanachokchai R, Kongtawelert P, Lertprasertsuke N, Matsushima T. Antimutagenicity of lemon grass ( Cymbopogon citratus Stapf) to various known mutagens in salmonella mutation assay. Mutat Res . 1994;341(1):71-75.
34. Suaeyun R, Kinouchi T, Arimochi H, Vinitketkumnuen U, Ohnishi Y. Inhibitory effects of lemon grass ( Cymbopogon citratus Stapf) on formation of azoxymethane-induced DNA adducts and abberant crypt foci in the rat colon. Carcinogenesis . 1997;18(5):949-955.
35. Vinitketkumnuen U, Chewonarin T, Dhumtanom P, Lertprasertsuk N, Wild CP. Aflatoxin-albumin adduct formation after single and multiple doses of aflatoxin B(1) in rats treated with Thai medicinal plants. Mutat Res . 1999;428(1-2):345-351.
36. Puatanachokchai R, Kishida H, Denda A, et al. Inhibitory effects of lemon grass ( Cymbopogon citratus Stapf) extract on the early phase of hepatocarcinogenesis after initiation with diehtylnitrosamine in male Fischer 344 rats. Cancer Lett . 2002;183(1):9-15.
37. Dubey N, et al. Cytotoxicity of the essential oils of Cymbopogon citratus and Ocium gratissimum . Indian J Pharm Sci . 1997;59:263-264.
38. Dubey N, et al. Citral: a cytotoxic principle isolated from the essential oil of Cymbopogon citratus against P388 leukemia cells. Curr Sci . 1997;73:22-24.
39. Kumar A, Malik F, Bhushan S, et al. An essential oil and its major constituent isointermedeol induce apoptosis by increased expression of mitochondrial cytochrome c and apical death receptors in human leukaemia HL-60 cells. Chem Biol Interact . 2008;171(3):332-347.
40. Nakamura Y, Miyamoto M, Murakami A, Ohigashi H, Osawa T, Uchida K. A phase ΙΙ detoxification enzyme inducer from lemongrass: identification of citral and involvement of electrophilic reaction in the enzyme induction. Biochem Biophys Res Commun . 2003;302(3):593-600.
41. Lorenzetti BB, Souza GE, Sarti SJ, Santos Filho D, Ferreira SH. Myrcene mimics the peripheral analgesic activity of lemongrass tea. J Ethnopharmacol . 1991;34(1):43-48.
42. Carbajal D, Casaco A, Arruzazabala L, Gonzalez R, Tolon Z. Pharmacological study of Cymbopogon citratus leaves. J Ethnopharmacol . 1989;25(1):103-107.
43. Rao VS, Menezes AM, Viana GS. Effect of myrcene on nociception in mice. J Pharm Pharmacol . 1990;42(12):877-878.
44. Carlini EA, Contar J de DP, Silva-Filho AR, da Silveira-Filho NG, Frochtengarten ML, Bueno OF. Pharmacology of lemongrass ( Cymbopogon citratus Stapf.). I. Effects of teas prepared from the leaves on laboratory animals. J Ethnopharmacol . 1986;17(1):37-64.
45. Menut C, et al. Aromatic plants of Tropical West Africa. XI. Chemical composition, antioxidant and antiradical properties of the essential oils of three Cymbopogon species from Burkina Faso. J Essent Oil Res . 2000;12:207-212.
46. Gazola R, Machado D, Ruggiero C, Singi G, Macedo Alexandre M. Lippia alba , Melissa officinalis and Cymbopogon citratus : effects of the aqueous extracts on the isolated hearts of rats. Pharmacol Res . 2004;50(5):477-480.
47. Adeneye AA, Agbaje EO. Hypoglycemic and hypolipidemic effects of fresh leaf aqueous extract of Cymbopogon citratus Stapf. in rats. J Ethnopharmacol . 2007;112(3):440-444.
48. Oyedele AO, Gbolade AA, Sosan MB, Adewoyin FB, Soyelu OL, Orafidiya OO. Formulation of an effective mosquito-repellent topical product from lemongrass oil. Phytomedicine . 2002;9(3):259-262.
49. Ahmad F, et al. Repellancy of essential oils against the domiciliary cockroach, Periplanta americana . Insect Sci Its Appl . 1995;16:391-393.
50. Gilbert B, Teixeira DF, Carvalho ES. Activities of the Pharmaceutical Technology Institute of the Oswaldo Cruz Foundation with medicinal, insecticidal and insect repellant plants. An Acad Bras Cienc . 1999;71(2):265-271.
51. Fandohan P, Gnonlonfin B, Laleye A, Gbenou JD, Darboux R, Moudachirou M. Toxicity and gastric tolerance of essential oils from Cymbopogon citratus , Ocimum gratissimum and Ocimum basilicum in Wistar rats. Food Chem Toxicol . 2008;46(7):2493-2497.
52. Williams GO, Omoh LE. Mitotic effects of the aqueous leaf extract of Cymbopogon citratus in Allium cepa root tips. Cytobios . 1996;87(350):161-168.
53. De-Oliveira AC, Ribeiro-Pinto LF, Paumgartten JR. In vitro inhibition of CYP2B1 monooxygenase by beta-myrcene and other monoterpenoid compounds. Toxicol Lett . 1997;92(1):39-46.
54. De-Oliveira AC, Ribeiro-Pinto LF, Otto SS, Goncalves A, Paumgartten FJ. Induction of liver monooxygenase by beta-myrcene. Toxicology . 1997;124(2):135-140.
55. Souza Formigoni ML, Lodder HM, Gianotti Filho O, Ferreira TM, Carlini EA. Pharmacology of lemongrass ( Cymbopogon citratus Stapf). II. Effects of daily two month administration in male and female rats and in offspring exposed "in utero". J Ethnopharmacol . 1986;17(1):65-74.
56. Orisakwe OE, Chilaka KC, Okpogba AN. Plasma levels of aluminum after lemon-grass ( Cymbopogon citratus ) ingestion in healthy volunteers. Asia Pac J Pharmacol . 1998;13:79-82.
57. Zamith HP, Vidal MN, Speit G, Paumgartten FJ. Absence of genotoxic activity of beta-myrcene in the in vivo cytogenetic bone marow assay. Braz J Med Biol Res . 1993;26(1):93-98.
58. Kauderer B, Zamith H, Paumgartten FJ, Speit G. Evaluation of the mutagenicity of beta-myrcene in mammalian cells in vitro. Environ Mol Mutagen . 1991;18(1):28-34.

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