Generic Name: guanabenz (GWAN a benz)Brand Names: Wytensin
What is guanabenz?
Guanabenz lowers blood pressure by decreasing the levels of certain chemicals in the blood. This allows the blood vessels (veins and arteries) to relax (widen).
Guanabenz is used to treat hypertension (high blood pressure).
Guanabenz may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about guanabenz?Do not stop taking this medication without first talking to your doctor. Stopping suddenly may make your condition worse. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
What should I discuss with my healthcare provider before taking guanabenz?You should not use guanabenz if you are allergic to it.
To make sure you can safely take guanabenz, tell your doctor if you have any of these other conditions:
liver disease (especially cirrhosis)-
kidney disease, or if you are on dialysis-
heart disease- or
a recent history of heart attack or stroke.
How should I take guanabenz?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Guanabenz is usually taken 2 times each day. Follow your doctor's instructions.
Your blood pressure will need to be checked often. Visit your doctor regularly.Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Do not stop taking this medication without first talking to your doctor. Stopping suddenly may make your condition worse. Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include extreme drowsiness, irritability, weak pulse, or fainting.
What should I avoid while taking guanabenz?This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.Avoid drinking alcohol. Guanabenz can increase the effects of alcohol.
Guanabenz side effectsGet emergency medical help if you have any of these signs of an allergic reaction: hives- difficult breathing- swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:
very slow heart rate-
chest pain, severe headache, ringing in your ears- or
feeling like you might pass out.
Less serious side effects may include:
dry mouth- or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Guanabenz Dosing Information
Usual Adult Dose for Hypertension:
Initial dose: 4 mg orally twice a day, whether used alone or in combination with a thiazide diuretic.Maintenance dose: 4 to 8 mg orally twice a day. The maximum dose studied is 32 mg twice a day, although doses this high are rarely needed.
What other drugs will affect guanabenz?Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by guanabenz. Tell your doctor if you regularly use any of these medicines, or any other blood pressure medications.
This list is not complete and other drugs may interact with guanabenz. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about guanabenz.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.